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Press Release

Proprietary Chinese medicine found containing western drug ingredients

5 February 2007

The Department of Health (DH) today (February 5) urged members of the public not to buy or use a proprietary Chinese medicine called ????????? (Xiaokeshuping Jiangtangning Jiaonang) which was found to have contained undeclared western drug ingredients that may cause side effects.

A DH spokesman said the department obtained samples of the product for investigation after the Hospital Authority reported a case in which a 79-year-old woman who had consumed the product was admitted to United Christian Hospital last October because of hypoglycaemic attack (low blood sugar level). She had recovered and been discharged from hospital. She obtained the product from the Mainland.

The spokesman said the department has no record of the product having been imported in to Hong Kong for sale.

Upon laboratory analysis, the product was found to have contained western drug ingredients of phenformin (????), rosiglitazone (????) and glibenclamide (????).

Phenformin was used previously for the management of diabetes. However, phenformin was associated with high incidence of lactic acidosis (buildup of lactic acid in the blood) which could be fatal. The drug was banned in Hong Kong in 1985.

Rosiglitazone and glibenclamide are western drug ingredients used for the management of diabetes which should be used under medical supervision. The known side-effects of rosiglitazone are headache, dizziness, and lower limb oedema (excessive accumulation of fluid) and those of glibenclamide are nausea and gastro-intestinal upset. Rosiglitazone should not be used in those with a history of heart failure.

Products containing these drug ingredients are Third Schedule poisons under the Pharmacy and Poisons Ordinance, i.e. they can only be sold on a doctor�

05 February 2007